Epidemiological data show increase of influenza and other ARI activity in Russia in comparison with previous week. The nationwide ILI & ARI morbidity level (68.5 per 10 000 of population) was lower than the national baseline (69.5) by 1.4%.
ILI and ARI epidemic thresholds were exceeded in two of 61 cities collaborating with two WHO NICs in Russia.
Exceeding of morbidity epidemic thresholds for overall population
- No data
- less 20%
- 20 - 49%
- 50% and more
Cumulative number of diagnosed influenza cases
Cumulative results of influenza laboratory diagnosis by different tests were submitted by 54 RBLs and two WHO NICs. According to these data as a result of 2160 patients investigation the overall proportion of respiratory samples positive for influenza was estimated as 0.3%, including 0.2% for influenza A(H3N2) virus and 0.05% for influenza type A virus.
Results of influenza diagnosis
- No data
- No detection
- H1pdm09
- H1pdm09+H1
- H1pdm09+B
- H1pdm09+B+H1
Influenza Virus Antigen Detection by Immunofluorescence Assay (IFA)
- B
- A(H1N1) + A(H1N1)pdm09
- A(H3N2)
- PIV
- AD
- RS
Influenza Virus RNA Detection by RT-PCR
- B
- A(H1N1)
- A(H3N2)
- A(H1N1)pdm09
- PIV
- AD
- RS
Table 1.
Influenza Virus Isolation
Base lab.
Number of investigated patients
Number of viruses isolated
H1
H3
B
H1pdm09
Untyped virus
Total
BL of RII
40
0
0
0
0
0
0
(%)
0,0
0,0
0,0
0,0
0,0
0,0
BL of IV
0
0
0
0
0
0
0
(%)
-
-
-
-
-
-
TOTAL
40
0
0
0
0
0
0
(%)
0,0
0,0
0,0
0,0
0,0
0,0
Table 2.
Influenza Virus Antigen Detection by Immunofluorescence Assay (IFA)
Base lab.
Number of investigated patients
Influenza
Parainfluenza
AD
RS
Total
H1+H1pdm09
H3
B
I
II
III
BL of RII
708
0
0
0
17
13
35
58
33
156
(%)
0,0
0,0
0,0
2,4
1,8
4,9
8,2
4,7
22,0
BL of IV
114
0
0
0
6
3
17
10
5
41
(%)
0,0
0,0
0,0
5,3
2,6
14,9
8,8
4,4
36,0
TOTAL
822
0
0
0
23
16
52
68
38
197
(%)
0,0
0,0
0,0
2,8
1,9
6,3
8,3
4,6
24,0
Table 3.
Influenza Virus RNA Detection by RT-PCR
Base lab.
Number of investigated patients
Influenza
PIV
AD
RS
A (not subtyped)
H1
H3
H5
B
H1pdm09
BL of RII
1392
1 / 1602
0 / 445
4 / 654
0 / 435
0 / 1392
0 / 696
31 / 1020
42 / 1008
82 / 999
(%)
0,06
0,0
0,6
0,0
0,0
0,0
3,0
4,2
8,2
BL of IV
236
0 / 236
0 / 58
1 / 58
0 / 58
0 / 236
0 / 58
2 / 177
15 / 177
12 / 177
(%)
0,0
0,0
1,7
0,0
0,0
0,0
1,1
8,5
6,8
TOTAL
1628
1 / 1838
0 / 503
5 / 712
0 / 493
0 / 1628
0 / 754
33 / 1197
57 / 1185
94 / 1176
(%)
0,05
0,0
0,7
0,0
0,0
0,0
2,8
4,8
8,0
Table 4.
Cumulative number of diagnosed influenza cases
Base lab.
Number of investigated patients
Number of diagnosed influenza cases
H1
H1+H1pdm09 (IFA)
H3
A (not subtyped)
B
H1pdm09
Total
BL of RII
1884
0
0
4
1
0
0
5
(%)
0,0
0,0
0,2
0,05
0,0
0,0
0,3
BL of IV
276
0
0
1
0
0
0
1
(%)
0,0
0,0
0,4
0,0
0,0
0,0
0,4
TOTAL
2160
0
0
5
1
0
0
6
(%)
0,0
0,0
0,2
0,05
0,0
0,0
0,3
Conclusion
Influenza and ARI morbidity data. Increased influenza and other ARI activity was registered during the week 50.2017 in traditional surveillance system in Russia. The nationwide ILI & ARI morbidity level (68.5 per 10 000 of population) was lower than the national baseline by 1.4%.
Etiology of ILI & ARI morbidity. The overall proportion of respiratory samples tested positive for influenza was estimated as 0.3%, including 0.2% for influenza A(H3N2) virus and 0.05% for influenza type A virus. Percent of positive ARI cases of non-influenza etiology (PIV, adeno- and RSV) was estimated as 24.0% of investigated patients by IFA and 15.6%by PCR.
Antigenic characterization. Five influenza A(H3N2) strains were antigenically related to influenza A/Hong Kong/4801/2014 virus.
Genetic characterization. One influenza A(H3N2) virus was characterized in Saint-Petersburg NIC. Virus belonged to genetic subgroup 3C.2a1 and was like A/Bolzano/07/2016 referens virus. 4 influenza A(H3N2) strains from clinical samples were characterized in Saint-Petersburg NIC. Viruses belonged to genetic subgroup 3C.2a and were like A/HongKong/4801/2014 referens virus.
In sentinel surveillance system clinical samples from 137 SARI and ILI/ARI patients were investigated by rRT-PCR. Only one influenza A(H3N2) case was detected among ILI/ARI patients.